Optimization of Curcumin Nanocrystals as Promising Strategy for Nose-to-Brain Delivery Application

Optimization of Curcumin Nanocrystals as Promising Strategy for Nose-to-Brain Delivery Application

Intranasal (IN) drug delivery is recognized to be an innovative strategy to deliver drugs to the Central Nervous System. One of the main limitations of IN dosing is the low volume of drug that can be administered. Accordingly, two requirements are necessary: the drug should be active at a low dosage...

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Bibliographic Details
Main Authors: Angela Bonaccorso, Maria Rosa Gigliobianco, Rosalia Pellitteri, Debora Santonocito, Claudia Carbone, Piera Di Martino, Giovanni Puglisi, Teresa Musumeci
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pharmaceutics
Subjects:
natural compound
experimental design
response surface methodology
sonoprecipitation
crystallinity
amorphism
Online Access:https://www.mdpi.com/1999-4923/12/5/476

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https://www.mdpi.com/1999-4923/12/5/476

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