Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection

Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection

Abstract Background Current World Health Organization guidelines for conducting anti-malarial drug efficacy clinical trials recommend genotyping Plasmodium falciparum genes msp1 and msp2 to distinguish recrudescence from reinfection. A more recently developed potential alternative to this method is...

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Bibliographic Details
Main Authors: Joseph Fulakeza, Sarah McNitt, Jimmy Vareta, Alex Saidi, Godfrey Mvula, Terrie Taylor, Don P. Mathanga, Dylan S. Small, Jacek Skarbinski, Julie R. Gutman, Karl Seydel
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
msp genotyping
24 SNP genotyping
Reinfection
Recrudescence
Online Access:http://link.springer.com/article/10.1186/s12936-019-2695-0

Internet

http://link.springer.com/article/10.1186/s12936-019-2695-0

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