Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
Abstract Background Accurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal measures such as heel quantitative speed of sound (SOS) and dual-energy X-ray absorptiometry bone mineral density are able to predict the risk of...
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | Genome Medicine |
Online Access: | https://doi.org/10.1186/s13073-021-00838-6 |