Predictive bioinformatics identifies novel regulators of proliferation in a cancer stem cell model

The cancer stem cell model postulates that tumors are hierarchically organized with a minor population, the cancer stem cells, exhibiting unlimited proliferative potential. These cells give rise to the bulk of tumor cells, which retain a limited ability to divide. Without successful targeting of can...

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Bibliographic Details
Main Authors: Evan Fields, Jonathan D. Wren, Constantin Georgescu, John R. Daum, Gary J. Gorbsky
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302398