STABILITY-INDICATING LC METHOD FOR THE QUANTIFICATION OF MIDAZOLAM ACTIVE PHARMACEUTICAL INGREDIENT AND IN PHARMACEUTICAL FORMULATIONS

STABILITY-INDICATING LC METHOD FOR THE QUANTIFICATION OF MIDAZOLAM ACTIVE PHARMACEUTICAL INGREDIENT AND IN PHARMACEUTICAL FORMULATIONS

A stability-indicating LC method was validated for the quantification of midazolam (MDZ) active pharmaceutical ingredient (API) and in pharmaceutical formulations. Isocratic chromatography was performed on C18 column with mobile phase containing methanol/acetonitrile/water (45:35:20 v/v/v) with 0.4%...

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Bibliographic Details
Main Authors: Daiane Anzilaggo, Bádila Regina Dalla Costa, Luciana Grazziotin Rossato-Grando, Hellen Karine Stulzer, Charise Dallazem Bertol
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2018-12-01
Series:Drug Analytical Research
Subjects:
forced degradation
hplc
injections
quality control
stress test
tablets
Online Access:https://seer.ufrgs.br/dar/article/view/86375/52028

Internet

https://seer.ufrgs.br/dar/article/view/86375/52028

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