Hfe deficiency impairs pulmonary neutrophil recruitment in response to inflammation.

Hfe deficiency impairs pulmonary neutrophil recruitment in response to inflammation.

Regulation of iron homeostasis and the inflammatory response are tightly linked to protect the host from infection. Here we investigate how imbalanced systemic iron homeostasis in a murine disease model of hereditary hemochromatosis (Hfe(-/-) mice) affects the inflammatory responses of the lung. We...

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Main Authors: Karolina Benesova, Maja Vujić Spasić, Sebastian M Schaefer, Jens Stolte, Tomi Baehr-Ivacevic, Katharina Waldow, Zhe Zhou, Ursula Klingmueller, Vladimir Benes, Marcus A Mall, Martina U Muckenthaler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3383765?pdf=render

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http://europepmc.org/articles/PMC3383765?pdf=render

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