Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains
Prion disease associated neurotoxicity is mainly attributed to PrP-scrapie (PrPSc), the disease associated isoform of a normal protein, the prion protein (PrPC). Participation of other proteins and processes is suspected, but their identity and contribution to the pathogenic process is unclear. Emer...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2012-03-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996111003871 |