Unraveling the Deleterious Effects of Cancer-Driven STK11 Mutants through Conformational Sampling Approach
Tumor suppressor gene, STK11 , encodes for serine-threonine kinase, which has a critical role in regulating cell growth and apoptosis. Mutations of the same lead to the inactivation of STK11, which eventually causes different types of cancer. In this study, we focused on identifying those driver mut...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2016-01-01
|
| Series: | Cancer Informatics |
| Online Access: | https://doi.org/10.4137/CIN.S38044 |