Mutant MAPK7-Induced Idiopathic Scoliosis is Linked to Impaired Osteogenesis
Background/Aims: Three rare MAPK7 variants that predispose individuals to adolescent idiopathic scoliosis have previously been identified. However, the mechanism underlying the effects of the mutations remain unknown. Methods: Human mesenchymal stem cells (hMSCs) were isolated from both patients and...
Main Authors: | Taifeng Zhou, Chong Chen, Caixia Xu, Hang Zhou, Bo Gao, Deying Su, Zhiheng Liao, Yongyong Li, Shulan Yang, Peiqiang Su |
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Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2018-07-01
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Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/491956 |
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