Cellular changes in motor neuron cell culture produced by cytotoxic cerebrospinal fluid from patients with amyotrophic lateral sclerosis

Introduction: The neurotoxic effects of cerebrospinal fluid (CSF) from patients with amyotrophic lateral sclerosis (ALS) have been reported by various authors who have attributed this neurotoxicity to the glutamate in CSF-ALS. Materials and methods: Cultures of rat embryonic cortical neurons were ex...

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Bibliographic Details
Main Authors: U. Gomez-Pinedo, M. Yáñez, J. Matías-Guiu, L. Galán, A. Guerrero-Sola, M.S. Benito-Martin, Á. Vela, J.A. Arranz-Tagarro, A.G. García
Format: Article
Language:English
Published: Elsevier España 2014-07-01
Series:Neurología (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2173580814000820