Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family

Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family

Reprogramming to pluripotency after overexpression of OCT4, SOX2, KLF4, and MYC is accompanied by global genomic and epigenomic changes. Histone modification and DNA methylation states in induced pluripotent stem cells (iPSCs) have been shown to be highly similar to embryonic stem cells (ESCs). Howe...

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Bibliographic Details
Main Authors: Eriona Hysolli, Yoshiaki Tanaka, Juan Su, Kun-Yong Kim, Tianyu Zhong, Ralf Janknecht, Xiao-Ling Zhou, Lin Geng, Caihong Qiu, Xinghua Pan, Yong-Wook Jung, Jijun Cheng, Jun Lu, Mei Zhong, Sherman M. Weissman, In-Hyun Park
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116300698

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http://www.sciencedirect.com/science/article/pii/S2213671116300698

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