Precision and linearity targets for validation of an IFNγ ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides

Precision and linearity targets for validation of an IFNγ ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides

<p>Abstract</p> <p>Background</p> <p>Single-cell assays of immune function are increasingly used to monitor T cell responses in immunotherapy clinical trials. Standardization and validation of such assays are therefore important to interpretation of the clinical trial d...

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Main Authors: Lyerly Herbert K, Clay Timothy M, Morse Michael A, Ghanayem Manar, Comatas Karrie, Summers Amanda, Payne Janice K, Hassler Jeffrey, Maecker Holden T, Bhatia Sonny, Ghanekar Smita A, Maino Vernon C, delaRosa Corazon, Disis Mary L
Format: Article
Language:English
Published: BMC 2008-03-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/9

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http://www.biomedcentral.com/1471-2172/9/9

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