The Potential Effect of Nav1.8 in Autism Spectrum Disorder: Evidence From a Congenital Case With Compound Heterozygous SCN10A Mutations

The Potential Effect of Nav1.8 in Autism Spectrum Disorder: Evidence From a Congenital Case With Compound Heterozygous SCN10A Mutations

Apart from the most prominent symptoms in Autism spectrum disorder (ASD), namely deficits in social interaction, communication and repetitive behavior, patients often show abnormal sensory reactivity to environmental stimuli. Especially potentially painful stimuli are reported to be experienced in a...

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Bibliographic Details
Main Authors: Björn Heinrichs, Baowen Liu, Jin Zhang, Jannis E. Meents, Kim Le, Andelain Erickson, Petra Hautvast, Xiwen Zhu, Ningbo Li, Yi Liu, Marc Spehr, Ute Habel, Markus Rothermel, Barbara Namer, Xianwei Zhang, Angelika Lampert, Guangyou Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
SCN10A/Nav1.8
autism spectrum disorder
p.I1511M
p.R512∗
genetic
mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.709228/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2021.709228/full

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