rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections

rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections

Hepatitis B virus infection is a serious global health problem and causes life-threatening liver disease. In particular, genotype C shows high prevalence and severe liver disease compared with other genotypes. However, the underlying mechanisms regarding virological traits still remain unclear. This...

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Bibliographic Details
Main Authors: So-Young Lee, Yu-Min Choi, Song-Ji Oh, Soo-Bin Yang, JunHyeok Lee, Won-Hyeok Choe, Yoon-Hoh Kook, Bum-Joon Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
hepatitis B virus
HBV e antigen (HBeAg) negative infection
genotype C
mitochondrial stress
type I interferons
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01735/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01735/full

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