Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation

Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation

Dendritic cells (DCs) are antigen (Ag)-presenting cells that activate and stimulate effective immune responses by T cells, but can also act as negative regulators of these responses and thus play important roles in immune regulation. Pro-angiogenic vascular endothelial growth factor (VEGF) has been...

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Bibliographic Details
Main Authors: Luciana Cavalheiro Marti, Lorena Pavon, Patricia Severino, Tatiana Sibov, Daiane Guilhen, Carlos Alberto Moreira-Filho
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2014-02-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
indoleamine-pyrrole 2,3-dioxygenase
dendritic cell
vascular endothelial growth factor A
tolerance
immune
lymphocytes
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000100070&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000100070&lng=en&tlng=en

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