Anomalous Scaling of Gene Expression in Confined Cell-Free Reactions

Abstract Cellular surface breaks the symmetry of molecular diffusion across membrane. Here, we study how steric interactions between the surface and the bulk of cell-sized emulsion droplets alters gene expression emulated by a cell-free transcription/translation (TXTL) system. The concentration of s...

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Bibliographic Details
Main Authors: Ryota Sakamoto, Vincent Noireaux, Yusuke T. Maeda
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25532-3