Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

Background: Given the unceasing worldwide surge in COVID-19 cases, there is an imperative need to develop highly specific and sensitive serology assays to define exposure to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Methods: Pooled plasma samples from PCR positive COVID-19 patien...

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Bibliographic Details
Main Authors: Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Bernett Lee, Siew-Wai Fong, Barnaby Edward Young, Rhonda Sin-Ling Chee, Nicholas Kim-Wah Yeo, Anthony Torres-Ruesta, Guillaume Carissimo, Chek Meng Poh, Zi Wei Chang, Matthew Zirui Tay, Yi-Hao Chan, Mark I-Cheng Chen, Jenny Guek-Hong Low, Paul A. Tambyah, Shirin Kalimuddin, Surinder Pada, Seow-Yen Tan, Louisa Jin Sun, Yee-Sin Leo, David C. Lye, Laurent Renia, Lisa F.P. Ng
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:EBioMedicine
Subjects:
Epitopes
SARS-CoV-2
COVID-19
Patients
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302863

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http://www.sciencedirect.com/science/article/pii/S2352396420302863

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