Differential Kinase Activation in Peripheral Blood Mononuclear Cells from Non-Small-Cell Lung Cancer Patients Treated with Nivolumab

Differential Kinase Activation in Peripheral Blood Mononuclear Cells from Non-Small-Cell Lung Cancer Patients Treated with Nivolumab

In the era of precision medicine, research of biomarkers for identification of responders to nivolumab therapy is a major challenge. Peripheral blood mononuclear cells (PBMC) could be an interesting surrogate tissue for identifying pharmacodynamic biomarkers. The aim of this exploratory study was to...

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Bibliographic Details
Main Authors: Gaëlle Noé, Audrey Bellesoeur, Lisa Golmard, Audrey Thomas-Schoemann, Pascaline Boudou-Rouquette, Manuela Tiako Meyo, Alicja Puszkiel, Jennifer Arrondeau, Jérome Alexandre, François Goldwasser, Benoit Blanchet, Michel Vidal
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
nivolumab
kinome
PBMC
non-small-cell lung cancer
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/11/6/762

Internet

https://www.mdpi.com/2072-6694/11/6/762

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