Next-Generation Sequencing in Order to Better Characterize a BRCA Variant of Uncertain Significance
BRCA germline mutations are the most common predisposing factor in familial breast-ovarian cancer syndrome families. However, many screened patients are identified as harboring BRCA variants of uncertain significance (VUS), rather than carrying deleterious germline mutations [Calo et al.: Cancers 20...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2017-07-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/478005 |