A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ

Cannabinoid receptors (CB) are expressed throughout human skin epithelium. CB1 activation inhibits human hair growth and decreases proliferation of epidermal keratinocytes. Since psoriasis is a chronic hyperproliferative, inflammatory skin disease, it is conceivable that the therapeutic modulation o...

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Bibliographic Details
Main Authors: Yuval Ramot, Koji Sugawara, Nóra Zákány, Balázs I. Tóth, Tamás Bíró, Ralf Paus
Format: Article
Language:English
Published: PeerJ Inc. 2013-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/40.pdf