Epoxide Syntheses and Ring-Opening Reactions in Drug Development

Epoxide Syntheses and Ring-Opening Reactions in Drug Development

This review concentrates on success stories from the synthesis of approved medicines and drug candidates using epoxide chemistry in the development of robust and efficient syntheses at large scale. The focus is on those parts of each synthesis related to the substrate-controlled/diastereoselective a...

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Bibliographic Details
Main Authors: Fotini Moschona, Ioanna Savvopoulou, Maria Tsitopoulou, Despoina Tataraki, Gerasimos Rassias
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Catalysts
Subjects:
epoxides
drug development
catalytic asymmetric epoxidation
organocatalysis
process development and manufacturing routes
Sharpless and Jacobsen–Katsuki asymmetric epoxidation
Online Access:https://www.mdpi.com/2073-4344/10/10/1117

Internet

https://www.mdpi.com/2073-4344/10/10/1117

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