Natural selection and genetic diversity of domain I of Plasmodium falciparum apical membrane antigen-1 on Bioko Island

Natural selection and genetic diversity of domain I of Plasmodium falciparum apical membrane antigen-1 on Bioko Island

Abstract Background Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a promising candidate antigen for a blood-stage malaria vaccine. However, antigenic variation and diversity of PfAMA-1 are still major problems to design a universal malaria vaccine based on this antigen, especially aga...

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Bibliographic Details
Main Authors: Ya-Nan Wang, Min Lin, Xue-Yan Liang, Jiang-Tao Chen, Dong-De Xie, Yu-Ling Wang, Carlos Salas Ehapo, Urbano Monsuy Eyi, Hui-Ying Huang, Jing-Li Wu, Dan-Yan Xu, Zhi-Mao Chen, Yi-Long Cao, Hai-Bin Chen
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Malaria Journal
Subjects:
Bioko Island
Plasmodium falciparum
AMA-1
Domain I
Natural selection
Genetic diversity
Online Access:http://link.springer.com/article/10.1186/s12936-019-2948-y

Internet

http://link.springer.com/article/10.1186/s12936-019-2948-y

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