Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain

Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain

Abstract Background Cell therapy is proposed to be a potential treatment for Parkinson’s disease (PD). Although fetal retinal pigment epithelial (RPE) cells have been tested in trials for treating PD patients, controversy has been raised over the issue of whether such cells can be reprogrammed into...

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Bibliographic Details
Main Authors: Sha Li, Han Zhang, Aifang Wang, Yan Liu, Houqi Liu, Feng Yue, Xianmixinuer Abulaiti, Caiqiao Zhang, Lingsong Li
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Medicine
Subjects:
Cell-replacement therapy
Parkinson’s disease
Retinal pigment epithelium
Chemically induced reprogramming
Online Access:http://link.springer.com/article/10.1186/s10020-019-0076-3

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http://link.springer.com/article/10.1186/s10020-019-0076-3

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