Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence

Using a valid chronic mild stress (CMS) model of depression, we found that adolescent (postnatal days [PND] 28–41) CMS induced transient alterations in anhedonia that did not persist into adulthood after a 3-week recovery period. Previously stressed adult rats exhibited more immobility/despair behav...

Full description

Bibliographic Details
Main Authors: Yu Zhang, Feng Shao, Qiong Wang, Xi Xie, Weiwen Wang
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2017/9382797