Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation[S]

Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation[S]

In mammals, white adipose tissue (WAT) stores and releases lipids, whereas brown adipose tissue (BAT) oxidizes lipids to fuel thermogenesis. In obese individuals, WAT undergoes profound changes; it expands, becomes dysfunctional, and develops a low-grade inflammatory state. Importantly, BAT content...

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Bibliographic Details
Main Authors: Petra Kotzbeck, Antonio Giordano, Eleonora Mondini, Incoronata Murano, Ilenia Severi, Wiebe Venema, Maria Paola Cecchini, Erin E. Kershaw, Giorgio Barbatelli, Guenter Haemmerle, Rudolf Zechner, Saverio Cinti
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Lipid Research
Subjects:
brown fat
white adipose tissue
white adipocyte
adipose triglyceride lipase
adipocyte size
macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033114X

Internet

http://www.sciencedirect.com/science/article/pii/S002222752033114X

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