Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells

Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells

The balance of hematopoietic stem cell (HSC) self-renewal and differentiation is critical for a healthy blood supply; imbalances underlie hematological diseases. The importance of HSCs and their progenitors have led to their extensive characterization at genomic and transcriptomic levels. However, t...

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Bibliographic Details
Main Authors: Balyn W Zaro, Joseph J Noh, Victoria L Mascetti, Janos Demeter, Benson George, Monika Zukowska, Gunsagar S Gulati, Rahul Sinha, Ryan A Flynn, Allison Banuelos, Allison Zhang, Adam C Wilkinson, Peter Jackson, Irving L Weissman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
stem cell
hematopoiesis
mass spectromtetry
proteomics
Online Access:https://elifesciences.org/articles/62210

Internet

https://elifesciences.org/articles/62210

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