Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy

Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy

T cell immunotherapy is a concept developed for the treatment of cancer and infectious diseases, based on cytotoxic T lymphocytes to target tumor- or pathogen-specific antigens. Antigen-specificity of the T cell receptors (TCRs) is an important selection criterion in the developmental design of immu...

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Bibliographic Details
Main Authors: Chai Fen Soon, Shihong Zhang, Pothakamuri Venkata Suneetha, Dinler Amaral Antunes, Michael Peter Manns, Solaiman Raha, Christian Schultze-Florey, Immo Prinz, Heiner Wedemeyer, Margaret Sällberg Chen, Markus Cornberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
CD8+ T cells
cross-reactivity
T cell therapy
immunotherapy
T cell receptor (TCR)
TCR redirection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02076/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02076/full

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