Natural compound sanguinarine chloride targets the type III secretion system of Salmonella enterica Serovar Typhimurium

The type III secretion system (T3SS) is a key virulence mechanism of many Gram-negative bacterial pathogens. Upon contact between bacteria and host cells, T3SS transfers a series of effectors from the bacterial cytosol to host cells. It is widely known that a mutation in T3SS does not impair bacteri...

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Bibliographic Details
Main Authors: Yong Zhang, Yan Liu, Tingting Wang, Xuming Deng, Xiao Chu
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818300530