Metabolic fate and organ distribution of 13C-3′-sialyllactose and 13C-N-acetylneuraminic acid in wild-type mice – No evidence for direct incorporation into the brain

Metabolic fate and organ distribution of 13C-3′-sialyllactose and 13C-N-acetylneuraminic acid in wild-type mice – No evidence for direct incorporation into the brain

Milk sialyllactose (SL) and sialic acids (SA) are considered to be crucial for brain composition and development. To investigate their metabolic fate, we administered 13C-labelled 3′SL (13C-3′SL) and 13C-N-acetylneuraminic acid (13C-Neu5Ac) to NMRI mice. From per oral and intravenous (i.v.) applicat...

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Bibliographic Details
Main Authors: Christina E. Galuska, Silvia Rudloff, Sabine Kuntz, Christian Borsch, Martina Reutzel, Gunter Eckert, Sebastian P. Galuska, Clemens Kunz
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Functional Foods
Subjects:
3′ sialyllactose
N-acetylneuraminic acid
Stable isotopes
Metabolism
Brain
Wildtype mice
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620304928

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http://www.sciencedirect.com/science/article/pii/S1756464620304928

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