The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome – a transcriptomic and proteomic approach

The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome – a transcriptomic and proteomic approach

Abstract Background and aims Dicarbonyl stress plays an important role in the pathogenesis of microvascular complications that precede the formation of advanced glycation end products, and contributes to the development of renal dysfunction. In renal cells, toxic metabolites like methylglyoxal lead...

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Bibliographic Details
Main Authors: Irena Markova, Martina Hüttl, Olena Oliyarnyk, Tereza Kacerova, Martin Haluzik, Petr Kacer, Ondrej Seda, Hana Malinska
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Nutrition & Metabolism
Subjects:
Metabolic syndrome
Methylglyoxal
Kidney dysfunction
Transcriptomics
Proteomics
Metabolomics
Online Access:http://link.springer.com/article/10.1186/s12986-019-0376-1

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http://link.springer.com/article/10.1186/s12986-019-0376-1

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