LncRNAs Participate in Post-Resuscitation Myocardial Dysfunction Through the PI3K/Akt Signaling Pathway in a Rat Model of Cardiac Arrest and Cardiopulmonary Resuscitation

LncRNAs Participate in Post-Resuscitation Myocardial Dysfunction Through the PI3K/Akt Signaling Pathway in a Rat Model of Cardiac Arrest and Cardiopulmonary Resuscitation

In this study, we aimed to explore the role of lncRNAs in post-resuscitation myocardial dysfunction in a rat model of CA-CPR. A rat model of CA-CPR was constructed using a VF method. Myocardial functions, including cardiac output (CO), ejection fraction (EF), and myocardial performance index (MPI),...

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Bibliographic Details
Main Authors: Jingying Hou, Chaotao Zeng, Guanghui Zheng, Lian Liang, Longyuan Jiang, Zhengfei Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
cardiopulmonary resuscitation
cardiac arrest
post-resuscitation myocardial dysfunction
long non-coding RNAs
competitive endogenous RNA
PI3K/Akt signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.689531/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.689531/full

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