Rusty Microglia: Trainers of Innate Immunity in Alzheimer's Disease

Rusty Microglia: Trainers of Innate Immunity in Alzheimer's Disease

Alzheimer's disease, the most common form of dementia, is marked by progressive cognitive and functional impairment believed to reflect synaptic and neuronal loss. Recent preclinical data suggests that lipopolysaccharide (LPS)-activated microglia may contribute to the elimination of viable neur...

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Bibliographic Details
Main Authors: Adonis Sfera, Roberto Gradini, Michael Cummings, Eddie Diaz, Amy I. Price, Carolina Osorio
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neurology
Subjects:
inflammasomes
astrocytes
microglia
exosomes
trained immunity
tolerized immunity
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01062/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.01062/full

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