Pethidine’s Half-life Alterations following Orthopedic Surgery: Is Available Literature Always Compatible with the Data Obtained at the Bedside?

Background:  It is suggested that surgery results in changes in kinetic profile of some medication. The aim of this study was to investigate possible alterations in pethidine’s half-life in postoperative pain management following orthopedic surgery of the inferior limb. Methods: Twelve patients who...

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Bibliographic Details
Main Authors: Shima Afhsar, Farshad Hashemian, Sasan Anari, Mahnaz Qomi, Mohammadreza Rouini
Format: Article
Language:English
Published: Research Center for Rational Use of Drugs (RCRUD) 2020-02-01
Series:Journal of Pharmaceutical Care
Subjects:
Online Access:https://jpc.tums.ac.ir/index.php/jpc/article/view/286