Adaptive immunity to human coronaviruses is widespread but low in magnitude

Adaptive immunity to human coronaviruses is widespread but low in magnitude

Abstract Objectives Endemic human coronaviruses (hCoVs) circulate worldwide but cause minimal mortality. Although seroconversion to hCoV is near ubiquitous during childhood, little is known about hCoV‐specific T‐cell memory in adults. Methods We quantified CD4 T‐cell and antibody responses to hCoV s...

Full description

Bibliographic Details
Main Authors: Hyon‐Xhi Tan, Wen Shi Lee, Kathleen M Wragg, Christina Nelson, Robyn Esterbauer, Hannah G Kelly, Thakshila Amarasena, Robert Jones, Graham Starkey, Bao Zhong Wang, Osamu Yoshino, Thomas Tiang, Michael Lindsay Grayson, Helen Opdam, Rohit D'Costa, Angela Vago, The Austin Liver Transplant Perfusionist Group, Laura K Mackay, Claire L Gordon, Adam K Wheatley, Stephen J Kent, Jennifer A Juno
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
CD4 T cell
coronavirus
cTFH
hCoV
lymph node
SARS‐CoV‐2
Online Access:https://doi.org/10.1002/cti2.1264

Internet

https://doi.org/10.1002/cti2.1264

Similar Items