HTRA1-Related Cerebral Small Vessel Disease: A Review of the Literature

HTRA1-Related Cerebral Small Vessel Disease: A Review of the Literature

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is clinically characterized by early-onset dementia, stroke, spondylosis deformans, and alopecia. In CARASIL cases, brain magnetic resonance imaging reveals severe white matter hyperintensities (WMH...

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Bibliographic Details
Main Authors: Masahiro Uemura, Hiroaki Nozaki, Taisuke Kato, Akihide Koyama, Naoko Sakai, Shoichiro Ando, Masato Kanazawa, Nozomi Hishikawa, Yoshinori Nishimoto, Kiran Polavarapu, Atchayaram Nalini, Akira Hanazono, Daisuke Kuzume, Akihiro Shindo, Mohammad El-Ghanem, Arata Abe, Aki Sato, Mari Yoshida, Takeshi Ikeuchi, Ikuko Mizuta, Toshiki Mizuno, Osamu Onodera
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neurology
Subjects:
heritability
vascular dementia
HTRA1
carriers
CARASIL
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00545/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00545/full

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