Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia

Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia

Abstract Background G6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative damage to red blood cells, leading to premature haemolysis. Treatment of Plasmodium vivax malaria with primaquine poses a potential risk of mild...

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Bibliographic Details
Main Authors: Eugenia Lo, Daibin Zhong, Beka Raya, Kareen Pestana, Cristian Koepfli, Ming-Chieh Lee, Delenasaw Yewhalaw, Guiyun Yan
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Malaria Journal
Subjects:
G6PD deficiency
Malaria
Plasmodium vivax
Primaquine
Genotype-phenotype
Ethiopia
Online Access:http://link.springer.com/article/10.1186/s12936-019-2981-x

Internet

http://link.springer.com/article/10.1186/s12936-019-2981-x

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