Successful treatment with osimertinib and its subsequent resistance mechanism in a patient with non-small-cell lung cancer harboring acquired EGFR T790M mutation after recovery from AC0010-induced interstitial lung disease

Successful treatment with osimertinib and its subsequent resistance mechanism in a patient with non-small-cell lung cancer harboring acquired EGFR T790M mutation after recovery from AC0010-induced interstitial lung disease

Hanping Wang,1 Li Zhang,1 Xiaohua Shi,2 Xiaotong Zhang,1 Xiaoyan Si11Department of Respiratory Medicine, Peking Union Medical College Hospital, Beijing 100730, People’s Republic of China; 2Department of Pathology, Peking Union Medical College Hospital, Beijing 100730, People’s Re...

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Bibliographic Details
Main Authors: Wang H, Zhang L, Shi X, Zhang X, Si X
Format: Article
Language:English
Published: Dove Medical Press 2019-07-01
Series:OncoTargets and Therapy
Subjects:
Osimertinib
AC0010
interstitial lung disease
resistance mechanism
transformation
large-cell neuroendocrine carcinoma
Online Access:https://www.dovepress.com/successful-treatment-with-osimertinib-and-its-subsequent-resistance-me-peer-reviewed-article-OTT

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https://www.dovepress.com/successful-treatment-with-osimertinib-and-its-subsequent-resistance-me-peer-reviewed-article-OTT

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