Targeting TF-AKT/ERK-EGFR Pathway Suppresses the Growth of Hepatocellular Carcinoma

Targeting TF-AKT/ERK-EGFR Pathway Suppresses the Growth of Hepatocellular Carcinoma

Tissue factor (TF) is a transmembrane glycoprotein to initiate blood coagulation and frequently overexpressed in a variety of tumors. Our previous study has showed that the expression of TF is upregulated and correlated with prognosis in hepatocellular carcinoma (HCC). However, the role and molecula...

Full description

Bibliographic Details
Main Authors: Shan-Zhou Huang, Meng-Ning Wei, Jia-Rong Huang, Zi-Jian Zhang, Wen-Ji Zhang, Qi-Wei Jiang, Yang Yang, Huan-Yu Wang, Hui-Lin Jin, Kun Wang, Zi-Hao Xing, Meng-Ling Yuan, Yao Li, Xiao-Shun He, Zhi Shi, Qi Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
tissue factor
epidermal growth factor receptor
AKT/ERK
tumor growth
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00150/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00150/full

Similar Items