Cholesterol improves the transfection efficiency of polyallylamine as a non-viral gene delivery vector

ABSTRACT Cationic polymers such as polyallylamine (PAA) having primary amino groups are poor transfection agents and possess a high cytotoxicity index when used without any chemical modification. In this study, PAA was modified with cholesterol in order to improve transfection efficiency and to redu...

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Bibliographic Details
Main Authors: Reza Kazemi Oskuee, Mahdieh Ramezanpour, Leila Gholami, Bizhan Malaekeh-Nikouei
Format: Article
Published: Universidade de São Paulo 2017-10-01
Series:Brazilian Journal of Pharmaceutical Sciences
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