Neuronal Gamma-Aminobutyric Acid (GABA) Type A Receptors Undergo Cognate Ligand Chaperoning in the Endoplasmic Reticulum by Endogenous GABA

Neuronal Gamma-Aminobutyric Acid (GABA) Type A Receptors Undergo Cognate Ligand Chaperoning in the Endoplasmic Reticulum by Endogenous GABA

GABAA receptors mediate fast inhibitory neurotransmission in the brain. Dysfunction of these receptors is associated with various psychiatric/neurological disorders and drugs targeting this receptor are widely used therapeutic agents. Both the efficacy and plasticity of GABAA receptor-mediated neuro...

Full description

Bibliographic Details
Main Authors: Ping eWang, Randa S Eshaq, Charlie K. Meshul, Cynthia eMoore, Rebecca L. Hood, Nancy Jo Leidenheimer
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Calnexin
Endoplasmic Reticulum
GABA
trafficking
GABAA receptor
Immunogold Labeling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00188/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00188/full

Similar Items