The NMR structure of human obestatin in membrane-like environments: insights into the structure-bioactivity relationship of obestatin.

The NMR structure of human obestatin in membrane-like environments: insights into the structure-bioactivity relationship of obestatin.

The quest for therapeutic applications of obestatin involves, as a first step, the determination of its 3D solution structure and the relationship between this structure and the biological activity of obestatin. On this basis, we have employed a combination of circular dichroism (CD), nuclear magnet...

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Bibliographic Details
Main Authors: Begoña O Alén, Lidia Nieto, Uxía Gurriarán-Rodríguez, Carlos S Mosteiro, Juan C Álvarez-Pérez, María Otero-Alén, Jesús P Camiña, Rosalía Gallego, Tomás García-Caballero, Manuel Martín-Pastor, Felipe F Casanueva, Jesús Jiménez-Barbero, Yolanda Pazos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3464274?pdf=render

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http://europepmc.org/articles/PMC3464274?pdf=render

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