Is the efficacy of antidepressants in panic disorder mediated by adverse events? A mediational analysis.

It has been hypothesised that the perception of adverse events in placebo-controlled antidepressant clinical trials may induce patients to conclude that they have been randomized to the active arm of the trial, leading to the breaking of blind. This may enhance the expectancies for improvement and t...

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Bibliographic Details
Main Authors: Irene Bighelli, Anna Borghesani, Corrado Barbui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5456299?pdf=render