The efficacy and safety of valproic acid medications with controlled active ingredient release in adults in real clinical practice from the position of pharmacokinetic and pharmacogenetic approaches

The efficacy and safety of valproic acid medications with controlled active ingredient release in adults in real clinical practice from the position of pharmacokinetic and pharmacogenetic approaches

Objective: to analyze the efficacy and tolerability of sustained-release sodium valproate (SV) in adult patients with focal or generalized epilepsy in real clinical practice in three regions (Krasnoyarsk, Moscow, and Samara) of the Russian Federation.Patients and methods. The investigation enrolled...

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Bibliographic Details
Main Authors: P. N. Vlasov, N. V. Orekhova, M. V. Antonyuk, N. V. Filatova, N. A. Schnaider, D. V. Dmitrenko, S. N. Zobova, I. E. Poverennova, A. V. Yakunina, V. A. Kalinin, S. K. Zyryanov, I. F. Tishchenkova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2017-06-01
Series:Nevrologiâ, Nejropsihiatriâ, Psihosomatika
Subjects:
sustained-release sodium valproate
valproic acid
focal epilepsy
idiopathic generalized epilepsy
efficacy
tolerability
unwanted side reactions
cyp2c9, cyp2c9*1/*1, cyp2c9*2, cyp2c9*3, cyp2c9*2/*3 polymorphisms
Online Access:https://nnp.ima-press.net/nnp/article/view/721

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https://nnp.ima-press.net/nnp/article/view/721

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