The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis.

The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis.

The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease is still under debate. It remains disputed whether Treg suppress T cell-mediated hepatitis in vivo and whether hepatic regulatory T cells are functional in patients with autoimmune hepatitis.We used TF-OVA mice, which express...

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Bibliographic Details
Main Authors: Ira An Haack, Katja Derkow, Mathias Riehn, Marc-Nicolas Rentinck, Anja A Kühl, Seija Lehnardt, Eckart Schott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4658037?pdf=render

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http://europepmc.org/articles/PMC4658037?pdf=render

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