CIRCULATING ANTIBODIES TO ERYTHROPOIETIN ARE ASSOCIATED WITH LOWER EFFICACY OF RECOMBINANT EPOETIN TREATMENT IN PATIENTS UNDERGOING HAEMODIALYSIS
Biological preparations (BP) obtained by gene engineering possess a special characteristic called immunogenicity, i.e. propensity of biological drugs to induce an undesired immune response associated with arising anti-drug antibodies. These antibodies can change BP pharmacokinetics and pharmacodynam...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
SPb RAACI
2018-01-01
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Series: | Medicinskaâ Immunologiâ |
Subjects: | |
Online Access: | https://www.mimmun.ru/mimmun/article/view/1440 |