Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids.

The bioactive sphingolipid sphingosine 1-phosphate (S1P) is found in increased amounts in the airways of asthmatics. S1P can regulate airway smooth muscle functions associated with asthmatic inflammation and remodeling, including cytokine secretion. To date however, whether S1P induces secretion of...

Full description

Bibliographic Details
Main Authors: Md Mostafizur Rahman, Hatem Alkhouri, Francesca Tang, Wenchi Che, Qi Ge, Alaina J Ammit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3960248?pdf=render