Connective tissue growth factor (CTGF/CCN2) is negatively regulated during neuron-glioblastoma interaction.

Connective-tissue growth factor (CTGF/CCN2) is a matricellular-secreted protein involved in complex processes such as wound healing, angiogenesis, fibrosis and metastasis, in the regulation of cell proliferation, migration and extracellular matrix remodeling. Glioblastoma (GBM) is the major malignan...

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Bibliographic Details
Main Authors: Luciana F Romão, Fabio A Mendes, Natalia M Feitosa, Jane Cristina O Faria, Juliana M Coelho-Aguiar, Jorge Marcondes de Souza, Vivaldo Moura Neto, José Garcia Abreu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561339?pdf=render