The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status.

We aimed to evaluate the effects of the G-allele of rs6232 and the C-allele of rs6235 within PCSK1 on measures of body fat and glucose homeostasis in Danish individuals and to assess interactions of genotypes with age, sex and glucose tolerance status. Data were included in meta-analyses of addition...

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Bibliographic Details
Main Authors: Anette P Gjesing, Marie A Vestmar, Torben Jørgensen, Martin Heni, Jens J Holst, Daniel R Witte, Torben Hansen, Oluf Pedersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3173365?pdf=render