<i>TP53</i> in Myelodysplastic Syndromes: Recent Biological and Clinical Findings

<i>TP53</i> in Myelodysplastic Syndromes: Recent Biological and Clinical Findings

<em>TP53</em> dysregulation plays a pivotal role in the molecular pathogenesis of myelodysplastic syndromes (MDS), identifying a subgroup of patients with peculiar features. In this review we report the recent biological and clinical findings of <em>TP53</em>-mutated MDS, foc...

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Bibliographic Details
Main Authors: Cosimo Cumbo, Giuseppina Tota, Luisa Anelli, Antonella Zagaria, Giorgina Specchia, Francesco Albano
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
TP53 mutation, p53 expression, myelodysplastic syndrome, del(5q), prognosis, target therapy
Online Access:https://www.mdpi.com/1422-0067/21/10/3432

Internet

https://www.mdpi.com/1422-0067/21/10/3432

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