Composite macroH2A/NRF-1 Nucleosomes Suppress Noise and Generate Robustness in Gene Expression

Composite macroH2A/NRF-1 Nucleosomes Suppress Noise and Generate Robustness in Gene Expression

The histone variant macroH2A (mH2A) has been implicated in transcriptional repression, but the molecular mechanisms that contribute to global mH2A-dependent genome regulation remain elusive. Using chromatin immunoprecipitation sequencing (ChIP-seq) coupled with transcriptional profiling in mH2A knoc...

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Bibliographic Details
Main Authors: Matthieu D. Lavigne, Giannis Vatsellas, Alexander Polyzos, Evangelia Mantouvalou, George Sianidis, Ioannis Maraziotis, Marios Agelopoulos, Dimitris Thanos
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471500409X

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http://www.sciencedirect.com/science/article/pii/S221112471500409X

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